Gram-negative bacteria with a curved rod shape (motile with polar flagella).
Facultative anaerobes that test positive for oxidase.
Several species are pathogenic and are frequently linked to foodborne infection
– gastroenteritis (usually associated with eating undercooked seafood).
V. cholerae (the causative agent of cholera).
Important considerations: The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions. Generally, the most common agents/regimens are listed first. Listed dosages may need to be adjusted for renal dysfunction.
Doxycycline 300 mg orally x 1 (single dose). [Effective as Tetracycline 500mg q6h x 3 days based on stool output, duration of diarrhea, hydration requirements, etc.]
Azithromycin 1 gram orally x 1 OR 500mg orally once daily for 3 days.
Erythromycin 250-500 mg orally three times daily for x 3 days
Ciprofloxacin 1 gram (single dose). Other regimens listed. Not as effective as agents listed above.