Widely distributed in nature and are mostly innocuous.
C. diphtheriae: pathogen responsible for diphtheria.
Pleomorphic through their life cycles: occur in various lengths and frequently have thickenings at either end, depending on the surrounding conditions.
Important considerations: The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions. Generally, the most common agents/regimens are listed first. Listed dosages may need to be adjusted for renal dysfunction. Note: antibiotic therapy and diphtheria antitoxin for severe cases.
Erythromycin 500 mg four times daily for 14 days
Penicillin G (25,000 to 50,000 units/kg to a max of 1.2 million units IV q12h until patient can take oral medicine), then Penicillin VK 250 – 500mg orally q6h. Total treatment course – 14 days