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Chlamydophila psittaci

Background:

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Atypical Organisms
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>Chlamydophila pneumoniae
>Chlamydophila psittaci led
>Coxiella burnetii
>Legionella species ( L. pneumophila)
>Mycoplasma pneumonia

Chlamydophila psittaci

  • -lethal intracellular bacterial species (may cause endemic avian chlamydiosis, and respiratory psittacosis)
  • -Psittacosis often starts with flu-like symptoms and becomes a life-threatening pneumonia.

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Therapy:

Important considerations:  The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions.   Generally, the most common agents/regimens are listed first.  Adjust length of therapy based on clinical course

  1. Doxycycline 100mg orally or IV twice daily x 7 to 21 days
  2. Minocycline:   (IV/oral): 200 mg x 1,  followed by 100mg q12h x 10-14 days
  3. Azithromycin  500mg orally x 1 then 250mg  once daily for 4 days  OR  250-500 mg once daily for 7 days.
  4. Clarithromycin 500mg orally twice daily x 10-14 days
  5. Levofloxacin 750 mg IV/PO once daily  x 10-14 days  (not as well studied).

Chlamydophila psittaci