normal human oral and vaginal flora and are the predominant anaerobic, Gram-negative bacilli recovered from anaerobic infections of the respiratory tract (include aspiration pneumonia, lung abscesses, and chronic otitis media and sinusitis).
Prevotella species have been recovered also from abscesses and burns around the oral cavity, human bites, paronychia, urinary tract infection, brain abscesses, osteomyelitis and bacteremia associated with upper respiratory tract infections.
Play a major role in the pathogenesis of periodontal disease and periodontal abscesses. The prevalence of Prevotela melaninogenics is high in the dental plaque of persons with Down syndrome.
Important considerations: The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions. Generally, the most common agents/regimens are listed first.