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Sinusitis
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| Sinusitis |
Possible therapeutic alternatives |
| Sinusitis (Acute) symptoms < 4 weeks.
Usual duration of therapy: 10-14 days
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Common pathogens |
| Augmentin 875/125 mg orally twice daily or 500/125mg three times daily or
Augmentin XR* 1000/62.5 mg 2 tablets orally twice daily.
*AUGMENTIN XR is contraindicated in patients with a creatinine clearance of < 30 mL/min. and in hemodialysis patients |
| Cefpodoxime (Vantin) 200mg twice daily x 10-14 days OR |
| Cefprozil (Cefzil) 500 mg orally twice daily OR |
| Ceftin (cefuroxime oral) 250mg orally twice daily or |
| Bactrim DS twice daily |
| Severe penicillin allergy: |
| Clarithromycin 500mg orally twice daily OR |
| Zithromax (Azithromycin) 500mg PO x 1, then 250mg PO qd x 4 days OR |
| Levofloxacin 750mg orally once daily |
| Drug resistant S.pneumo: |
| Levofloxacin 750mg orally once daily x 7-10 days |
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| Chronic sinusitis (symptoms > 3 months) |
Common pathogens |
| Same as above. Surgery may be required. Consider reserving antibiotic therapy for acute flares only. |
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| Sinusitis (Hospitalized patient) Intubated etc. |
Common pathogens |
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