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Pneumonia (VAP)
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Ventilator-associated pneumonia (VAP)
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| (Mild to moderate infection AND multi-drug resistance unlikely): |
Common pathogens |
Ceftriaxone 1-2 grams IV q24h OR
Ampicillin-sulbactam (Unasyn) 3.0 grams ivpb q6h OR
Levofloxacin 750 mg IV/PO once daily OR
Ertapenem 1 gm IV q24h
PLUS (If MRSA suspected)
Vancomycin - (patient-specific regimen - trough goal 15-20 mcg/ml) |
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| (Severe infection OR multi-drug resistance LIKELY): |
Common pathogens |
Cefepime 2 grams IV every 12 hours OR
Piperacillin-tazobactam 4.5 grams IV Q6H OR
Meropenem 1 gm IV q8h
PLUS
Vancomycin - (patient-specific regimen - trough goal 15-20 mcg/ml)
PLUS
Ciprofloxacin 400mg IV q8h OR
Levofloxacin 750 mg IV/PO once daily OR
Aminoglycoside (Tobra) - patient-specific regimen. |
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